CD104 Antilichaam [346-11A]

CD104 represents the integrin beta4 subunit that associates non-covalently with integrin alpha6 (CD49f) to form the alpha6beta4 integrin heterodimer. The alpha6beta4 complex is expressed on the basal surface of a variety of epithelial cell types particularly on stratified squamous epithelia. It is also found in peripheral nerves, in certain subsets of endothelial cells, and on immature thymocytes. It also has been found to be associated with a number of malignant tissues. Hemidesmosomal alpha6beta4 plays an important role in the adhesion of epithelial cells to basement membranes via interactions with laminin and/or kalinin anchoring filaments. It is not known if the monoclonal antibody 346-11A can block this adhesion.

192897

A2A863

A2A863

Mouse

Tumor-associated antigen TSP-180 purified from a transplantable BALB/c carcinoma

[346-11A]

Unconjugated

Primary Antibodies

Signal Transduction

0.5 mg/mL

Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

None

Blue Ice

Store vial at 2-8˚ C

IgG2a

CD104

CD104 Antibody [346-11A] for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, and immunoprecipitation assays.

Itgb4

Integrin beta 4

Mus musculus

Integrin beta4

IHC-P, IHC-Fr, ICC, Flow, IP

Liquid