CD106 Antilichaam (PE)

The STA monoclonal antibody specifically reacts with human CD106, a 110 kDA glycoprotein also named Vascular Cell Adhesion Molecule-1 (VCAM-1) and INCAM-110. Its expression is induced by inflammation stimuli and cytokines and it is found mainly on activated vascular endothelium. CD106 is also found on subsets of macrophages, stromal cells, dendritic cells, and myeloid lineage cells. The integrins that bind CD106 are CD49d/CD29 and LPAM-1, and it is involved in cell adhesion, transmigration and T cell proliferation.

2022

P17813

Human

STA

PE

Primary Antibodies

Immunology

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Batch dependent

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

None

Blue Ice

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Mouse IgG1, kappa

The STA monoclonal antibody specifically reacts with human CD106, a 110 kDA glycoprotein also named Vascular Cell Adhesion Molecule-1 (VCAM-1) and INCAM-110.

ENG

Endoglin

Homo sapiens

Elshal, M. F., Khan, S. S., Takahashi, Y., Solomon, M. A., McCoy, J. P. (2005) . CD146 (Mel-CAM), an adhesion marker of endothelial cells, is a novel marker of lymphocyte subset activation in normal peripheral blood.Blood,106 (8), 2923-2924.

Shih, I. M. (1999) . The role of CD146 (Mel‐CAM) in biology and pathology.The Journal of pathology,189 (1), 4-11.

Solovey, A. N., Gui, L., Chang, L., Enenstein, J., Browne, P. V., Hebbel, R. P. (2001) . Identification and functional assessment of endothelial P1H12.Journal of Laboratory and Clinical Medicine,138 (5), 322-331.

END, HHT1, ORW1, ENG

Flow

Liquid