CD107a Antilichaam [H4A3] (APC)

The H4A3 monoclonal antibody specifically reacts with human CD107a, a heavily glycosylated type I membrane glycoprotein. CD107a is also known as Lysosomal-associated membrane protein 1 (LAMP-1) and is widely expressed intracellular antigen. It can be found on the surface of PHA-activated lymphocytes, activated platelets, cytotoxic T cells, NK cells, macrophages, epithelial cells, endothelial cells, and some tumor lines. CD107a is a ligand for E-selectin and galaptin and is reported to be involved in cell adhesion and tumor metastasis.

3916

P11279

Human

H4A3

APC

Primary Antibodies

Innate Immunity

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Batch dependent

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

None

Blue Ice

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Mouse IgG1, kappa

The H4A3 monoclonal antibody specifically reacts with human CD107a, a heavily glycosylated type I membrane glycoprotein.

LAMP1

Lysosomal-associated membrane protein 1

Homo sapiens

Godfrey, D. I., Kennedy, J., Mombaerts, P., Tonegawa, S., Zlotnik, A. (1994) . Onset of TCR-beta gene rearrangement and role of TCR-beta expression during CD3-CD4-CD8-thymocyte differentiation. The Journal of Immunology,152 (10), 4783-4792.

Godfrey, D. I., Zlotnik, A. L. B. E. R. T., Suda, T. A. K. A. S. H. I. (1992) . Phenotypic and functional characterization of c-kit expression during intrathymic T cell development.The Journal of Immunology,149 (7), 2281-2285.

Feng, H., Sandlow, J. I., Sandra, A. (1998) . The c-kit receptor and its possible signaling transduction pathway in mouse spermatozoa.Molecular reproduction and development,49 (3), 317-326.

LAMPA, CD107a, LGP120, LAMP1

Flow

Liquid