CD11a Antilichaam [HI111]

The HI111 monoclonal antibody specifically reacts with human CD11a, a 180kDA glycoprotein. CD11a is the integrin alpha L chain that forms with CD18 the heterodimer molecule Lymphocyte Function-associated Antigen-1 (LFA-1) . LFA-1 is expressed on all leukocytes and is involved in intercellular adhesions. The heterodimer can bind to CD50 (ICAM-3), CD54 (ICAM-1), and CD102 (ICAM-2) .

3683

P20701

Human

HI111

Unconjugated

Primary Antibodies, Functional Antibodies

Cancer

The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.

Batch dependent

Phosphate-buffered aqueous solution, ph7.2.

None

Blue Ice

The product should be stored undiluted at 4˚ C . Do not freeze.

Mouse IgG1, kappa

The HI111 monoclonal antibody specifically reacts with human CD11a, a 180kDA glycoprotein.

ITGAL

Integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)

Homo sapiens

Inghirami, G., Wieczorek, R., Zhu, B. Y., Silber, R., Dalla-Favera, R., Knowles, D. M. (1988) . Differential expression of LFA-1 molecules in non-Hodgkin's lymphoma and lymphoid leukemia.Blood,72 (4), 1431-1434.

Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

Bochner, B. S., Luscinskas, F. W., Gimbrone, M. A., Newman, W., Sterbinsky, S. A., Derse-Anthony, C. P., ... Schleimer, R. P. (1991) . Adhesion of human basophils, eosinophils, and neutrophils to interleukin 1-activated human vascular endothelial cells: contributions of endothelial cell adhesion molecules.The Journal of experimental medicine,173 (6), 1553-1557.

CD11A, LFA-1, LFA1A, ITGAL

Flow, Functional Assays

Liquid