CD11b Antilichaam [3A33]

CD11b (integrin alphaM subunit) combines with CD18 (integrin beta2 subunit) to form the integrin Mac-1, also known as complement receptor 3 (CR3), which mediates adhesion to C3bi and ICAM-1 (CD54) . Mac-1 is expressed at varying levels on granulocytes, macrophages, dendritic cells, NK cells, and B-1 cells in the peritoneal and pleural cavities. In addition to its role in binding C3bi on opsonized targets and mediation of the subsequent ingestion process, Mac-1 is important as an adhesion molecule in the transendothelial migration of monocytes and neutrophils.

16409

P05555

P05555

Mouse

Peritoneal macrophages from B6D2 hybrid mice

[3A33]

Unconjugated

Primary Antibodies

Immunology, Neuroscience, Signal Transduction

0.5 mg/mL

Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

None

Blue Ice

Store vial at 2-8˚ C

IgG2a

CD11b

CD11b Antibody [3A33] for use in flow cytometry, immunohistochemistry / immunocytochemistry, immunoprecipitation, and blocking assays.

Itgam

Integrin alpha M

Mus musculus

Integrin alphaM, Mac-1alpha, Mac-1, Mo1, CR3, C3biR

ELISA, IHC-Fr, ICC, Flow

Liquid