CD11c Antilichaam [3.9]

The 3.9 monoclonal antibody specifically binds to the human adhesion glycoprotein CD11c, a 150 kDA integrin alpha chain also known as integrin alpha X. It is expressed on macrophages, granulocytes, monocytes, dendritic cells, natural killer cells, and subsets of B and T lymphocytes. The CD11c/CD18 complex associates with the iC3b, fibrinogen and ICAM-1 and has an important function in leukocyte adhesion.

3687

P20702

Human

3.9

Unconjugated

Primary Antibodies

Innate Immunity

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Batch dependent

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

None

Blue Ice

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Mouse IgG1, kappa

The 3.9 monoclonal antibody specifically binds to the human adhesion glycoprotein CD11c, a 150 kDA integrin alpha chain also known as integrin alpha X.

ITGAX

Integrin, alpha X (complement component 3 receptor 4 subunit)

Homo sapiens

Schlossman, S. F. (1995) .Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.

Knapp W (1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

McMichael, A. J. (1987) . Leucocyte typing III.Oxford University Press, Oxford. Norton AJ, Isaacson PG (1985)

Ottonello, L., Epstein, A. L., Dapino, P., Barbera, P., Morone, P., Dallegri, F. (1999) . Monoclonal Lym-1 antibody-dependent cytolysis by neutrophils exposed to granulocyte-macrophage colony-stimulating factor: intervention of Fc-gamma RII (CD32), CD11b-CD18 integrins, and CD66b glycoproteins.Blood,93 (10), 3505-3511.

CD11C, SLEB6, ITGAX

Flow, Functional Assays, IF, IP

Liquid