CD13 / ANPEP monoklonaal antilichaam

Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma.

ANPEP

P15144

Human

Recombinant Human CD13/ANPEP Protein

LAP; ANPEP; APN; CD13; GP150; LAP1; P150; PEPN; Aminopeptidase N; AP-M; AP-N; CD13 antigen; CD13APN; PEPNhAPN; gp150; Alanyl (membrane) aminopeptidase; Alanyl aminopeptidase; Aminopeptidase M; AMPN; AP M; AP N; CD 13; hAPN; LAP 1; Microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13

5A2

Unconjugated

WB; IHC-P

Immunology; Stem Cells

Protein A

1 mg/mL

WB 1:500-1:2000; IHC-P 1:100-1:500

0.2 μm filtered solution in PBS

Ice bag

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

https://789.bio/eb/8n6Z2kVt

110 kDa

140 kDa

IgG1