CD133 Antilichaam / PROM1

CD133/PROM1/Prominin-1 may play a role in cell differentiation, proliferation and apoptosis. Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner. [UniProt]

Western blot: 1:1000

O43490

Human

A human recombinant partial protein was used as the immunogen for this CD133 antibody.

6H10-F1-C11

WB

Protein G affinity

Purified

This CD133 antibody is available for research use only.

Store the CD133 antibody at -20°C.

In PBS with 50% glycerol, 0.1 mg/mL BSA and 0.02% sodium azide

The stated application concentrations are suggested starting points. Titration of the CD133 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Western blot testing of human CaCo2 cell lysate with CD133 antibody at 1:1000. Predicted molecular weight: ~97 kDa (unmodified), ~130 kDa (glycosylated) .