CD14 Antilichaam [5A3H5D5 (FC) / 5A3B11B5]

CD14 antigen is a GPI-linked glycoprotein with a molecular weight of 55kD. The CD14 antigen is expressed on cells of the myelomonocytic lineage including monocytes, macrophages and Langerhans cells. Low expression is observed on neutrophils and on human B cells. CD14 antigen is a receptor for bacterial lipopolysaccharide (LPS, endotoxin) and the lipopolysaccharide binding protein (LBP) . LBP and CD14 antigen serves two physiological roles. These proteins act as opsonin and opsonic receptor, respectively, to promote the phagocytic uptake of bacteria or LPScoated particles by macrophages.

929

P08571

P08571

Human

Ni-NTA purified recombinant human CD14 expressed in E. Coli strain BL21 (DE3) .

5A3H5D5 (FC) / 5A3B11B5

Unconjugated

Primary Antibodies

Innate Immunity

Batch dependent

Purified antibody in PBS containing 0.03% sodium azide.

None

Blue Ice

CD14 monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG1

CD14

CD14 molecule

Homo sapiens

J Mammary Gland Biol Neoplasia 2000, 5 : 227-241.

J Mammary Gland Biol Neoplasia 2000, 5 : 165-185.

Myeloid cell-specific leucine-rich glycoprotein

ELISA, IHC

20141203