CD158e1 Antilichaam [DX9]

CD158e1 is a 70 kDa transmembrane glycoprotein and a killer cell immunoglobulin (Ig) -like receptor (KIR) that is expressed on a subset of natural killer cells and T cells. The monoclonal antibody DX9 is expressed on a subset of CD3-, CD56+ NK cells isolated from peripheral blood at varying levels (<0.1% to 61%) among individuals but not on thymocytes, B lymphocytes, granulocytes, or monocytes. Interactions with CD158e1 and certain MHC HLA-B antigens on a target cell inhibits cytotoxicity, possibly preventing target cell lysis and death. KIR and MHC class I interactions may regulate NK and T cell response to antigen stimulation.

3811

P43629

P43629

Human, Baboon

Human NK clone VL186-1 (CD3-, CD16+, CD56+)

[DX9]

Unconjugated

Primary Antibodies

Immunology

0.1 mg/mL

Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

None

Blue Ice

Store vial at 2-8&#730; C

IgG1

CD158e1

CD158e1 Antibody [DX9] for use in flow cytometry, immunohistochemistry / immunocytochemistry, immunoprecipitation, and blocking assays.

KIR3DL1

Killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1

Homo sapiens

NKB1, p70, KIR, 3DL1, KIR3DL1, KIR3D, NKAT3

Flow

Liquid