CD16 Antilichaam [3G8] (FITC)

The 3G8 monoclonal antibody specifically reacts with human CD16, the low affinity IgG receptor III (FC gamma RIII) . CD16 is expressed on granulocytes, monocytes, macrophages, and NK cells and plays a role in NK activation and signal transduction. CD16 is expressed as either CD16a or CD16b. CD16a is a polypeptide-anchored transmembrane protein and CD16b is a glycosylphosphatidylinositol (GPI) -anchored protein that is expressed exclusively on neutrophils.

2214

P08637

Human

3G8

FITC

Primary Antibodies

Innate Immunity

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Batch dependent

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

None

Blue Ice

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Mouse IgG1, kappa

The 3G8 monoclonal antibody specifically reacts with human CD16, the low affinity IgG receptor III (FC gamma RIII) .

FCGR3A

Fc fragment of IgG, low affinity IIIa, receptor (CD16a)

Homo sapiens

Leucocyte Typing VI: White Cell Differentiation Antigens: Proceedings of the Sixth International Workshop and Conference Held in Kobe, Japan, 10-14 November 1996. Garland Pub., 1998.

Hayakawa, Y., Huntington, N. D., Nutt, S. L., Smyth, M. J. (2006) . Functional subsets of mouse natural killer cells.Immunological reviews,214 (1), 47-55.

Tittarelli, A., Mendoza-Naranjo, A., Faras, M., Guerrero, I., Ihara, F., Wennerberg, E., ... Salazar-Onfray, F. (2014) . Gap Junction Intercellular Communications Regulate NK Cell Activation and Modulate NK Cytotoxic Capacity.The Journal of Immunology,192 (3), 1313-1319.

CD16, FCG3, CD16A, FCGR3, IGFR3, IMD20, FCR-10, FCRIII, FCGRIII, FCRIIIA, FCGR3A

Flow

Liquid