CD161 Antilichaam (HP-3G10) (APC)

The HP-3G10 monoclonal antibody specifically binds to an 80 kDa homodimer type II membrane glycoprotein from the C-type lectin superfamily, known as the human CD161 or NKR-P1A. CD161 is expressed on most natural killer cells, subsets of CD4+ and CD8+ T lymphocytes, gammadelta TCR T lymphocytes, a subset of CD3+ thymocytes, and especially on CD45RO+ T lymphocytes. Reports indicate that it may serve as a specific receptor for some natural killer cell targets and a possible stimulatory role.

3820

Q12918

Human

HP-3G10

APC

Primary Antibodies

Innate Immunity, Immunology

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Batch dependent

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

None

Blue Ice

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Mouse IgG1, kappa

The HP-3G10 monoclonal antibody specifically binds to an 80 kDa homodimer type II membrane glycoprotein from the C-type lectin superfamily, known as the human CD161 or NKR-P1A.

KLRB1

Killer cell lectin-like receptor subfamily B, member 1

Homo sapiens

Barclay, A. N., Brown, M. H., Law, S. A. K. A., McKnight, A. J., Tomlinson, M. G., van der Merwe, P. A. (1997) .The leucocyte antigen factsbook. Academic Press.

Lindsten, T., Lee, K. P., Harris, E. S., Petryniak, B., Craighead, N., Reynolds, P. J., ... Gray, G. S. (1993) . Characterization of CTLA-4 structure and expression on human T cells.The Journal of Immunology,151 (7), 3489-3499.

Kuiper, H. M., Brouwer, M., Linsley, P. S., Van Lier, R. A. (1995) . Activated T cells can induce high levels of CTLA-4 expression on B cells.The Journal of Immunology,155 (4), 1776-1783.

NKR, CD161, CLEC5B, NKR-P1, NKRP1A, NKR-P1A, hNKR-P1A, KLRB1

Flow

Liquid