CD184 Antilichaam [2B11] (PE)

The 2B11 monoclonal antibody specifically reacts with mouse CD184 (CXCR4or Fusin), a seven-transmembrane G-protein-coupled receptor. It is expressed by astrocytes, B cells, T cells, monocytes, neutrophils, neurons, and hematopoietic cell types. CD184 is a coreceptor for X4 HIV-1.The monoclonal 2B11 antibody recognizes the amino terminus of CD184 and has functional activity.

12767

P70658

Mouse

2B11

PE

Primary Antibodies

Stem Cell, Chemokines & Cytokines, Growth Factors

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Batch dependent

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

None

Blue Ice

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Rat IgG2b, kappa

The 2B11 monoclonal antibody specifically reacts with mouse CD184 (CXCR4or Fusin), a seven-transmembrane G-protein-coupled receptor.

Cxcr4

Chemokine (C-X-C motif) receptor 4

Mus musculus

Pierelli, L., Bonanno, G., Rutella, S., Marone, M., Scambia, G., Leone, G. (2001) . CD105 (endoglin) expression on hematopoietic stem/progenitor cells.Leukemia lymphoma,42 (6), 1195-1206.

She, X., Matsuno, F., Harada, N., Tsai, H., Seon, B. K. (2004) . Synergy between anti‐endoglin (CD105) monoclonal antibodies and TGF‐-beta in suppression of growth of human endothelial cells.International journal of cancer,108 (2), 251-257.

Seon, B. K., Kumar, S. (2002) . CD105 antibody for targeting of tumor vascular endothelial cells. InThe new angiotherapy (pp. 499-515) . Humana Press.

CD184, LESTR, Sdf1r, Cmkar4, PB-CKR, b2b220Clo, PBSF/SDF-1

Flow

Liquid