CD197 Antilichaam [3D12] (PE)

The 3D12 monoclonal antibody specifically reacts with human CD197 (CCR7 or EBI-1), a seven-transmembrane G-protein-coupled. It is the receptor for the secondary lymphoid-tissue chemokine (SLC or 6CKine), CCL19, and CCL21. CD197 is expressed on subsets of B and T cells, and mature dendritic cells. The monoclonal 3D12 antibody recognizes the N-terminus of the receptor.

1236

P32248

Human

3D12

PE

Primary Antibodies

Immunology, Chemokines & Cytokines, Growth Factors

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Batch dependent

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

None

Blue Ice

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Mouse IgG1, kappa

The 3D12 monoclonal antibody specifically reacts with human CD197 (CCR7 or EBI-1), a seven-transmembrane G-protein-coupled.

CCR7

Chemokine (C-C motif) receptor 7

Homo sapiens

Gattei, V., Godeas, C., Degan, M., Rossi, F. M., Aldinucci, D., Pinto, A. (1999) . Characterization of anti‐CD138 monoclonal antibodies as tools for investigating the molecular polymorphism of syndecan‐1 in human lymphoma cells.British journal of haematology,104 (1), 152-162.

Fitzgerald, M. L., Wang, Z., Park, P. W., Murphy, G., Bernfield, M. (2000) . Shedding of syndecan-1 and-4 ectodomains is regulated by multiple signaling pathways and mediated by a TIMP-3sensitive metalloproteinase.The Journal of cell biology,148 (4), 811-824.

Itoua Maga, R., Lemieux, J., Roy, A., Simard, C., Nron, S. (2014) . Flow Cytometry Assessment of In Vitro Generated CD138.BioMed research international,2014.

BLR2, EBI1, CCR-7, CD197, CDw197, CMKBR7, CC-CKR-7, CCR7

Flow

Liquid