CD1C Mouse Monoclonal Antibody [Kloon ID: UMLBI46]

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known. [provided by RefSeq, Jul

Carrier-free (BSA/glycerol-free) CD1C mouse monoclonal antibody, clone UMLBI46

BDCA1; CD1; CD1A; R7

Homo sapiens CD1c molecule (CD1C), mRNA.

911

P29017

Unconjugated

Hematopoietic cell lineage

Hematopoietic cell lineage

IHC 1:100

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Transmembrane

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

CD1C

https://www.ncbi.nlm.nih.gov/gene/?term=911

https://www.uniprot.org/uniprot/P29017