CD1d Antilichaam [1B1]

The 1B1 monoclonal antibody specifically reacts with mouse CD1d, a 48kDA type I membrane glycoprotein with a structural homology to MHC class I molecules. CD1d is expressed by mouse leukocytes, epithelial cells, thymocytes, and dendritic cells and is the only molecules in the CD1 family to have been found in the mouse. The 1B1 antibody detects CD1d in association with the Beta2m molecule.

12479

P11609

Mouse

1B1

Unconjugated

Primary Antibodies

Innate Immunity

The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.

Batch dependent

Phosphate-buffered aqueous solution, ph7.2.

None

Blue Ice

The product should be stored undiluted at 4˚ C . Do not freeze.

Rat IgG2b, kappa

The 1B1 monoclonal antibody specifically reacts with mouse CD1d, a 48kDA type I membrane glycoprotein with a structural homology to MHC class I molecules.

Cd1d1

CD1d1 antigen

Mus musculus

Szalay, G., Ladel, C. H., Blum, C., Brossay, L., Kronenberg, M., Kaufmann, S. H. (1999) . Cutting edge: anti-CD1 monoclonal antibody treatment reverses the production patterns of TGF--beta-2 and Th1 cytokines and ameliorates listeriosis in mice.The Journal of Immunology,162 (12), 6955-6958.

Roark, J. H., Park, S. H., Jayawardena, J., Kavita, U., Shannon, M., Bendelac, A. (1998) . CD1. 1 expression by mouse antigen-presenting cells and marginal zone B cells.The Journal of Immunology,160 (7), 3121-3127.

Amano, M., Baumgarth, N., Dick, M. D., Brossay, L., Kronenberg, M., Herzenberg, L. A., Strober, S. (1998) . CD1 expression defines subsets of follicular and marginal zone B cells in the spleen: -beta-2-microglobulin-dependent and independent forms.The Journal of Immunology,161 (4), 1710-1717.

Cd1a, Cd1d, CD1.1, Ly-38, AI747460, Cd1d1

Flow, Functional Assays

Liquid