CD2 Antilichaam [RM2-5]

The RM2-5 monoclonal antibody specifically binds to mouse CD2, a member of the Ig superfamily and type I transmembrane glycoprotein. CD2 is expressed on B cells, T cells, NK cells, and thymocytes and its ligand is CD48. It may be involved in immunoregulation, thymocyte maturation, and T-cell activation. The RM2-5 antibody has been reported to block CD2 mediated cell to cell adhesion.

12481

P08920

Mouse

RM2-5

Unconjugated

Primary Antibodies

Immunology

The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.

Batch dependent

Phosphate-buffered aqueous solution, ph7.2.

None

Blue Ice

The product should be stored undiluted at 4˚ C . Do not freeze.

Rat IgG2b, lambda

The RM2-5 monoclonal antibody specifically binds to mouse CD2, a member of the Ig superfamily and type I transmembrane glycoprotein.

Cd2

CD2 antigen

Mus musculus

Yagita, H., Nakamura, T., Karasuyama, H., Okumura, K. (1989) . Monoclonal antibodies specific for murine CD2 reveal its presence on B as well as T cells.Proceedings of the National Academy of Sciences,86 (2), 645-649.

Nakamura, T. E. T. S. U. Y. A., Takahashi, K. A. Z. U. H. I. S. A., Fukazawa, T. O. H. R. U., Koyanagi, M. A. K. O. T. O., Yokoyama, A., Kato, H., ... Okumura, K. (1990) . Relative contribution of CD2 and LFA-1 to murine T and natural killer cell functions.The Journal of Immunology,145 (11), 3628-3634.

Kato, K., Koyanagi, M., Okada, H., Takanashi, T., Wong, Y. W., Williams, A. F., ... Yagita, H. (1992) . CD48 is a counter-receptor for mouse CD2 and is involved in T cell activation.The Journal of experimental medicine,176 (5), 1241-1249.

Ly37, LFA-2, Ly-37, Cd2

Flow

Liquid