CD20 Antilichaam [2H7] (APC)

The 2H7 monoclonal antibody specifically reacts with human CD20, a 33-37kDA B-lymphocyte surface molecule. CD20 is an unglycosylated four-transmembrane phosphoprotein expressed by B cells in all stage of development, except the final plasma cells. It has been reported that the molecule is involved in B cell activation and has also been observed on a subset of circulating T lymphocytes.

931

P11836

Human

2H7

APC

Primary Antibodies

Immunology

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Batch dependent

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

None

Blue Ice

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Mouse IgG2b, kappa

The 2H7 monoclonal antibody specifically reacts with human CD20, a 33-37kDA B-lymphocyte surface molecule.

MS4A1

Membrane-spanning 4-domains, subfamily A, member 1

Homo sapiens

Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

Polyak, M. J., Deans, J. P. (2002) . Alanine-170 and proline-172 are critical determinants for extracellular CD20 epitopes

Schlossman, S. F. (1995) .Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.

B1, S7, Bp35, CD20, CVID5, MS4A2, LEU-16, MS4A1

Flow

Liquid