CD20 Antilichaam [IISB12]

The AISB12 monoclonal antibody specifically reacts with mouse cd20, a 32kDA B-lymphocyte surface molecule. CD20 is expressed by B cells in all stage of development, except for the initial pro-B and final plasma cells. CD20 has no natural ligands and has an important role in enabling B cells to respond optimally to T-independent antigens. The AISB12 antibody binds to the extracellular loop domain of the CD20 molecule.

12482

P19437

Mouse

AISB12

Unconjugated

Primary Antibodies, Functional Antibodies

Immunology

The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.

Batch dependent

Phosphate-buffered aqueous solution, ph7.2.

None

Blue Ice

The product should be stored undiluted at 4˚ C . Do not freeze.

Rat IgG2a

The AISB12 monoclonal antibody specifically reacts with mouse cd20, a 32kDA B-lymphocyte surface molecule.

Ms4a1

Membrane-spanning 4-domains, subfamily A, member 1

Mus musculus

Uchida, J., Hamaguchi, Y., Oliver, J. A., Ravetch, J. V., Poe, J. C., Haas, K. M., Tedder, T. F. (2004) . The innate mononuclear phagocyte network depletes B lymphocytes through Fc receptordependent mechanisms during anti-CD20 antibody immunotherapy.The Journal of experimental medicine,199 (12), 1659-1669.

Uchida, J., Lee, Y., Hasegawa, M., Liang, Y., Bradney, A., Oliver, J. A., ... Tedder, T. F. (2004) . Mouse CD20 expression and function.International immunology,16 (1), 119-129.

Qian, J., Zheng, Y., Zheng, C., Wang, L., Qin, H., Hong, S., ... Yi, Q. (2012) . Active vaccination with Dickkopf-1 induces protective and therapeutic antitumor immunity in murine multiple myeloma.Blood,119 (1), 161-169.

Cd20, Ly-44, Ms4a2, AA960661, Ms4a1

Flow, Functional Assays

Liquid