CD21 Antilichaam [HB5] (FITC)

The HB5 monoclonal antibody specifically reacts with human CD21, a 145 kDA glycosylated type I integral membrane protein. CD21 is reported to be involved in B cell activation and proliferation. It is expressed on follicular dendritic cells, mature B cells, a subset of T cells, and a subset of epithelial cells. It is the receptor utilized by the Epstein-Barr virus to infect B cells.

1380

P20023

Human

HB5

FITC

Primary Antibodies

Immunology

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Batch dependent

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

None

Blue Ice

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Mouse IgG2a, kappa

The HB5 monoclonal antibody specifically reacts with human CD21, a 145 kDA glycosylated type I integral membrane protein.

CR2

Complement component (3d/Epstein Barr virus) receptor 2

Homo sapiens

Tedder, T. F., Clement, L. T., Cooper, M. D. (1984) . Expression of C3d receptors during human B cell differentiation: immunofluorescence analysis with the HB-5 monoclonal antibody.The Journal of Immunology,133 (2), 678-683.

Fingeroth, J. D., Weis, J. J., Tedder, T. F., Strominger, J. L., Biro, P. A., Fearon, D. T. (1984) . Epstein-Barr virus receptor of human B lymphocytes is the C3d receptor CR2.Proceedings of the National Academy of Sciences,81 (14), 4510-4514.

Nemerow, G. R., Wolfert, R. O. B. E. R. T., McNaughton, M. E., Cooper, N. R. (1985) . Identification and characterization of the Epstein-Barr virus receptor on human B lymphocytes and its relationship to the C3d complement receptor (CR2) .Journal of virology,55 (2), 347-351.

CR, C3DR, CD21, CVID7, SLEB9, CR2

Flow

Liquid