![CD22 Antilichaam [2D6] (PE)](/_ipx/q_80/productPlaceholder.webp)
CD22 Antilichaam [2D6] (PE)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
CD22, also known as Lyb-8, is a heterodimeric transmembrane glycoprotein and a member of a structurally related group of immunoglobulin (Ig) superfamily domain-containing proteins called the sialoadhesin family. It is detected in the cytoplasm early in B cell development (late pro-B cell stage), appears on the cell surface concomitant with IgD, and is found on most IgM+IgD+ mature B lymphocytes. Expression is lost with terminal differentiation of B cells and is absent on plasma cells. Activation of B cells via cross-linking of surface Ig increases CD22 expression. CD22 associates with the B cell receptor (BCR) complex and mediates intercellular adhesion. Its intracellular domain is phosphorylated after antigen receptor cross-linking and is involved in negative regulation of B cell activation.
12483
P35329
P35329
• Rat
Mouse
Splenic lymphocyte plasma membranes from CBA x C57 F1 mice
• Monoclonal
[2D6]
PE
Primary Antibodies
Cancer, Stem Cell, Immunology
0.1 mg/mL
Supplied in PBS/NaN3 and a stabilizing agent
None
Blue Ice
Store vial at 2-8˚ C
IgG1
CD22
CD22 Antibody [2D6] for use in flow cytometry assays.
Cd22
CD22 antigen
Mus musculus
Lyb-8, Leu-14, BL-CAM
WB, IHC-P, ICC, Flow
Liquid
Beschrijving
CD22 Antilichaam [2D6] (PE) Beschikbaar in 0.1 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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