CD23 Antilichaam [Tü1] (FITC)

CD23 is a 45 kDa type II integral membrane glycoprotein that is the low affinity receptor for IgE. It also binds to CD21 and the alpha chains of CD11b and CD11c. It is expressed by B cells and monocytes and, weakly, on T cells, follicular dendritic cells, eosinophils, NK cells, Langerhans cells, and platelets. It is upregulated in response to B cell activation, CD40 ligation, or in response to IL-4 or IL-13. CD23 is responsible for regulation of IgE synthesis and may play a role in antigen presentation by B cells and follicular dendritic cells by interacting with CD40.

2208

P06734

P06734

Human

Purified human tonsil lymphocytes

[Tü1]

FITC

Primary Antibodies

Immunology, Stem Cell, Cancer, Cell Cycle

Batch dependent

Supplied in PBS/NaN3

None

Blue Ice

Store vial at 2-8˚ C

IgG3

CD23

CD23 Antibody [Tü1] for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.

FCER2

Fc fragment of IgE, low affinity II, receptor for (CD23)

Homo sapiens

FCepsilonRII, B6, Leu-20, BLAST-2, low affinity IgE receptor

Flow, Separation

Liquid