CD24 Antilichaam [M1/69]

The M1/69 monoclonal antibody specifically reacts with mouse CD24, variably glycosylated GPI-anchored membrane protein. CD24 is known as the Heat Stable Antigen (HAS or HsAG) and is found on epithelial cells, thymocytes, monocytes, erythrocytes, granulocytes, dendritic cells and lymphocytes to the exclusion of NK cells. It is useful in delineating the stages of lymphocyte development and is involved in the costimulation of CD4+ T cells by B cells. CD62P (P-Selectin) is the reported ligand of CD24.

12484

P24807

Mouse

M1/69

Unconjugated

Primary Antibodies, Functional Antibodies

Immunology

The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.

Batch dependent

Phosphate-buffered aqueous solution, ph7.2.

None

Blue Ice

The product should be stored undiluted at 4˚ C . Do not freeze.

Rat IgG2b, kappa

The M1/69 monoclonal antibody specifically reacts with mouse CD24, variably glycosylated GPI-anchored membrane protein.

Cd24a

CD24a antigen

Mus musculus

Alterman, L. A., Crispe, I. N., Kinnon, C. (1990) . Characterization of the murine heat‐stable antigen: An hematolymphoid differentiation antigen defined by the J11d, M1/69 and B2A2 antibodies.European journal of immunology,20 (7), 1597-1602.

Crowley, M., Inaba, K., Witmer-Pack, M., Steinman, R. M. (1989) . The cell surface of mouse dendritic cells: FACS analyses of dendritic cells from different tissues including thymus.Cellular immunology,118 (1), 108-125.

Wenger, R. H., Rochelle, J. M., Seldin, M. F., Khler, G., Nielsen, P. J. (1993) . The heat stable antigen (mouse CD24) gene is differentially regulated but has a housekeeping promoter.Journal of Biological Chemistry,268 (31), 23345-23352.

HSA, Cd24, Ly-52, nectadrin, Cd24a

Flow, Functional Assays

Liquid