CD25 Antilichaam [BC96] (APC)

The BC96 monoclonal antibody specifically reacts with the 55 kDa type I transmembrane glycoprotein known as the interleukin-2 receptor alpha (IL-2R alpha, also known as CD25) . CD25 is expressed by the early progenitors of T and B lymphocytes lineage, and by activated mature T and B lymphocytes. CD25 is a low affinity interleukin-2 receptor, but its association with the IL-2 receptor beta chain (CD122) and the common gamma chain (CD 132) results in a high affinity IL-2R complex. CD25 plays an important role in B and T cell proliferation, differentiation, and activation.

3559

P01589

Human

BC96

APC

Primary Antibodies

Immunology

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Batch dependent

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

None

Blue Ice

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Mouse IgG1, kappa

The BC96 monoclonal antibody specifically reacts with the 55 kDa type I transmembrane glycoprotein known as the interleukin-2 receptor alpha (IL-2R alpha, also known as CD25) .

IL2RA

Interleukin 2 receptor, alpha

Homo sapiens

Schlossman, S., L. Bloumsell, et al. eds (1995) . Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York

Zhang, B., Zhang, X., Tang, F. L., Zhu, L. P., Liu, Y., Lipsky, P. E. (2008) . Clinical significance of increased CD4+ CD25 Foxp3+ T cells in patients with new-onset systemic lupus erythematosus.Annals of the rheumatic diseases,67 (7), 1037-1040.

Chapel, A., Bensussan, A., Vilmer, E., Dormont, D. (1992) . Differential human immunodeficiency virus expression in CD4+ cloned lymphocytes: from viral latency to replication.Journal of virology,66 (6), 3966-3970.

P55, CD25, IL2R, TCGFR, IDDM10, IL2RA

Flow

Liquid