CD27 Antilichaam [LG.3A10]

The LG.3A10 monoclonal antibody binds to CD27, 45kDA molecule in the Tumor Necrosis Factor Receptor (TNFR) superfamily. It is expressed on memory B cells, NK cells, mature T cells, and a subset of thymocytes. Cd27 is involved in the interactions between B and T cells through its ligand CD70. The LG.3A10 antibody is cross-reactive with human, mouse and rat CD27.

21940

P41272

Human, Mouse

LG.3A10

Unconjugated

Primary Antibodies, Functional Antibodies

Immunology, Apoptosis

The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.

Batch dependent

Phosphate-buffered aqueous solution, ph7.2.

None

Blue Ice

The product should be stored undiluted at 4˚ C . Do not freeze.

Armenian Hamster IgG

The LG.3A10 monoclonal antibody binds to CD27, 45kDA molecule in the Tumor Necrosis Factor Receptor (TNFR) superfamily.

Cd27

CD27 antigen

Mus musculus

Tesselaar, K., Xiao, Y., Arens, R., van Schijndel, G. M., Schuurhuis, D. H., Mebius, R. E., ... van Lier, R. A. (2003) . Expression of the murine CD27 ligand CD70 in vitro and in vivo.The journal of immunology,170 (1), 33-40.

Lee, E. M., Hurh, S., Cho, B., Oh, K. H., Kim, S. U., Surh, C. D., ... Ahn, C. (2013) . CD70-CD27 ligation between neural stem cells and CD4+ T cells induces Fas-FasL-mediated T cell death.Stem cell research therapy,4 (3), 56.

Gravestein, L. A., Nieland, J. D., Kruisbeek, A. M., Borst, J. (1995) . Novel mAbs reveal potent co-stimulatory activity of murine CD27.International immunology,7 (4), 551-557.

S152, Tp55, Tnfrsf7, Cd27

Flow, Functional Assays

Liquid