CD27 Antilichaam [O323] (APC)

The O323 monoclonal antibody specifically binds to the human CD27, which is a lymphocyte-specific member of the TNF/NGF-R family, expressed on a subset of human thymocytes and the majority of the mature T cells. CD27 is upregulated by T lymphocytes stimulation, and binds to CD70, enhancing the interaction between T and B lymphocytes. CD27 is a memory marker of B cells.

939

P26842

Human

O323

APC

Primary Antibodies

Immunology, Apoptosis

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Batch dependent

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

None

Blue Ice

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Mouse IgG1, kappa

The O323 monoclonal antibody specifically binds to the human CD27, which is a lymphocyte-specific member of the TNF/NGF-R family, expressed on a subset of human thymocytes and the majority of the mature T cells.

CD27

CD27 molecule

Homo sapiens

Knapp W (1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

Correia, D. V., Fogli, M., Hudspeth, K., da Silva, M. G., Mavilio, D., Silva-Santos, B. (2011) . Differentiation of human peripheral blood Vdelta-1+ T cells expressing the natural cytotoxicity receptor NKp30 for recognition of lymphoid leukemia cells.Blood,118 (4), 992-1001.

T14, S152, Tp55, TNFRSF7, S152. LPFS2, CD27

Flow

Liquid