CD282 Antilichaam [mT2.7] (FITC)

The mT2.7 monoclonal antibody specifically reacts with mouse CD282, the Toll-like receptor 2 (TLR2) . It is a type I transmembrane signaling receptor containing IL-1 receptor like intracellular domain and leucine-rich repeats (LRR) in the extracellular domain. CD282 is expressed on monocytes, macrophages, dendritic cells, and the RAW264.7 cell line and is involved distinguishing bacterial lipoproteins.

24088

Q9QUN7

Mouse

MT2.7

FITC

Primary Antibodies

Innate Immunity

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Batch dependent

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

None

Blue Ice

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Mouse IgG2a, kappa

The mT2.7 monoclonal antibody specifically reacts with mouse CD282, the Toll-like receptor 2 (TLR2) .

Tlr2

Toll-like receptor 2

Mus musculus

Mechetner, E. B., Roninson, I. B. (1992) . Efficient inhibition of P-glycoprotein-mediated multidrug resistance with a monoclonal antibody.Proceedings of the National Academy of Sciences,89 (13), 5824-5828.

Chaudhary, P. M., Mechetner, E. B., Roninson, I. B. (1992) . Expression and activity of the multidrug resistance P-glycoprotein in human peripheral blood lymphocytes [see comments].Blood,80 (11), 2735-2739.

Goda, K., Fenyvesi, F., Bacs, Z., Nagy, H., Mrin, T., Megyeri, A., ... Szab, G. (2007) . Complete inhibition of P-glycoprotein by simultaneous treatment with a distinct class of modulators and the UIC2 monoclonal antibody.Journal of Pharmacology and Experimental Therapeutics,320 (1), 81-88.

Ly105, Tlr2

Flow

Liquid