CD289 Antilichaam [M9.D6] (FITC)

The M9.D6 monoclonal antibody specifically reacts with mouse CD289 also known as toll-like receptor 9 (TLR9) . CD289 is involved in the activation of innate immunity, in acquired immune responses, and autoimmune diseases. It is involved in the immune system’s response to unmethylated CpG dinucleotide sequences such as those found in bacterial, viral, or synthetic DNA. CD289 assists in pathogen recognition and is expressed by subtypes of dendritic cells and B cells.

81897

Q9EQU3

Mouse

M9.D6

FITC

Primary Antibodies

Innate Immunity

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Batch dependent

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

None

Blue Ice

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Rat IgG2a

The M9.D6 monoclonal antibody specifically reacts with mouse CD289 also known as toll-like receptor 9 (TLR9) .

Tlr9

Toll-like receptor 9

Mus musculus

Walzer, T., Blry, M., Chaix, J., Fuseri, N., Chasson, L., Robbins, S. H., ... Vivier, E. (2007) . Identification, activation, and selective in vivo ablation of mouse NK cells via NKp46.Proceedings of the National Academy of Sciences,104 (9), 3384-3389.

Joncker, N. T., Fernandez, N. C., Treiner, E., Vivier, E., Raulet, D. H. (2009) . NK cell responsiveness is tuned commensurate with the number of inhibitory receptors for self-MHC class I: the rheostat model.The Journal of Immunology,182 (8), 4572-4580.

Gazit, R., Gruda, R., Elboim, M., Arnon, T. I., Katz, G., Achdout, H., ... Mandelboim, O. (2006) . Lethal influenza infection in the absence of the natural killer cell receptor gene Ncr1.Nature immunology,7 (5), 517-523.

B7-H, B7H1, PDL1, PD-L1, PDCD1L1, PDCD1LG1, Tlr9

Flow

Liquid