CD29 Antilichaam (TS2/16] (PE)

The TS2/16 moncolonal antibody specifically reacts with human CD29 (Integrin beta1), a 130 kDA type I glycoprotein expressed on hematopoietic and non-hematopoietic cells. It forms the VLA- (1-6) molecules with integrin alpha- (1-6) and is involved in the adhesion between cell-cell and cell-matrix. The TS2/16 antibody has been found to activate beta 1 integrins.

3688

P05556

Human

TS2/16

PE

Primary Antibodies

Cancer

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Batch dependent

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

None

Blue Ice

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Mouse IgG1, kappa

The TS2/16 moncolonal antibody specifically reacts with human CD29 (Integrin beta1), a 130 kDA type I glycoprotein expressed on hematopoietic and non-hematopoietic cells.

ITGB1

Integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)

Homo sapiens

Ridger, V. C., Wagner, B. E., Wallace, W. A., Hellewell, P. G. (2001) . Differential effects of CD18, CD29, and CD49 integrin subunit inhibition on neutrophil migration in pulmonary inflammation.The Journal of Immunology,166 (5), 3484-3490.

Noto, K., Kato, K., Okumura, K., Yagita, H. (1995) . Identification and functional characterization of mouse CD29 with a mAb.International immunology,7 (5), 835-842.

Sangaletti, S., Di Carlo, E., Gariboldi, S., Miotti, S., Cappetti, B., Parenza, M., ... Colombo, M. P. (2008) . Macrophage-derived SPARC bridges tumor cell-extracellular matrix interactions toward metastasis.Cancer research,68 (21), 9050-9059.

CD29, FNRB, MDF2, VLAB, GPIIA, MSK12, VLA-BETA, ITGB1

Flow

Liquid