CD3 Antilichaam [ACHT1]

CD3, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains ranging from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR) . CD3 is expressed on 70-80% of normal peripheral blood lymphocytes and on 10-20% of thymocytes. It plays a major role in signaling during antigen recognition, leading to T cell activation. The monoclonal antibody UCHT1 reacts with the 20 kDa epsilon chain of the CD3/TCR complex.

916

P07766

P07766

Human

Human peripheral blood lymphocytes from a patient with Sézary's syndrome and infant thymocytes

[UCHT1]

Unconjugated

Primary Antibodies

Cancer, Immunology, Signal Transduction

0.1 mg/mL

Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

None

Blue Ice

Store vial at 2-8˚ C

IgG1

CD3

CD3 Antibody [UCHT1] for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, immunoprecipitation, activation, and blocking assays.

CD3E

T-cell surface glycoprotein CD3 epsilon chain

Homo sapiens

CD3epsilon, T3E, TCRE, Leu-4, T3

Flow

Liquid