CD3 Antilichaam [SK7] (PE-Cy7)

The SK7 monoclonal antibody specifically reacts with the epsilon chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains gamma, delta, and epsilon chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction. The SK7 antibody is reported to have a mitogenic effect on the majority of peripheral blood T cells in the presence of functional monocytes.

916

P07766

Human

SK7

PE-Cy7

Primary Antibodies

Immunology

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Batch dependent

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

None

Blue Ice

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Mouse IgG1, kappa

The SK7 monoclonal antibody specifically reacts with the epsilon chain of the CD3/T lymphocyte antigen receptor complex.

CD3E

CD3e molecule, epsilon (CD3-TCR complex)

Homo sapiens

Van Dongen, J. J., Krissansen, G. W., Wolvers-Tettero, I. L., Comans-Bitter, W. M., Adriaansen, H. J., Hooijkaas, H., ... Terhorst, C. (1988) . Cytoplasmic expression of the CD3 antigen as a diagnostic marker for immature T-cell malignancies.Blood,71 (3), 603-612.

Haynes, B. F. (1986) . Summary of T cell studies performed during the second international workshop and conference on human leukocyte differentiation antigens. InLeukocyte typing II (pp. 3-30) . Springer New York.

Kap, Y. S., van Meurs, M., van Driel, N., Koopman, G., Melief, M. J., Brok, H. P., ... A't Hart, B. (2009) . A monoclonal antibody selection for immunohistochemical examination of lymphoid tissues from non-human primates.Journal of Histochemistry Cytochemistry,57 (12), 1159-1167.

T3E, TCRE, IMD18, CD3E

Flow

Liquid