CD30 Antibody [mCD30.1]

The mCD301 monoclonal antibody specifically binds to mouse CD30, a member of the Tumor Necrosis Factor Receptor (TNFR) superfamily. It is expressed on activated T, B, NK, and monocyte cells. Its expression on activated T lymphocytes is regulated by cytokines and CD28. The ligand for CD30 is CD153. It has been suggested that the molecule plays a role in the protection against autoimmunity and the regulation of Th1 and Th2 cytokine secretion.

21941

Q60846

Mouse

MCD30.1

Unconjugated

Primary Antibodies, Functional Antibodies

Apoptosis

The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.

Batch dependent

Phosphate-buffered aqueous solution, ph7.2.

None

Blue Ice

The product should be stored undiluted at 4˚ C . Do not freeze.

Armenian Hamster IgG

The mCD301 monoclonal antibody specifically binds to mouse CD30, a member of the Tumor Necrosis Factor Receptor (TNFR) superfamily.

Tnfrsf8

Tumor necrosis factor receptor superfamily, member 8

Mus musculus

Siegmund, T., Armitage, N., Wicker, L. S., Peterson, L. B., Todd, J. A., Lyons, P. A. (2000) . Analysis of the mouse CD30 gene: a candidate for the NOD mouse type 1 diabetes locus Idd9. 2.Diabetes,49 (9), 1612-1616.

Falini, B., Pileri, S., Pizzolo, G., D, H., Flenghi, L., Stirpe, F., ... Stein, H. (1995) . CD30 (Ki-1) molecule: a new cytokine receptor of the tumor necrosis factor receptor superfamily as a tool for diagnosis and immunotherapy.BLOOD-NEW YORK-,85, 1-1.

Heath, W. R., Kurts, C., Caminschi, I., Carbone, F. R., Miller, J. F. (1999) . CD 30 prevents T‐cell responses to non‐lymphoid tissues.Immunological reviews,169 (1), 23-29.

Ki, Cd30, Ki-1, D1S166E, Tnfrsf8

Flow, Functional Assays

Liquid