CD31 Antilichaam [390]

The 390 monoclonal antibody specifically reacts with mouse cd31, a 130-140 kDA type I transmembrane glycoprotein also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1) . CD31 is reported to bind to CD38 and is expressed on platelets, monocytes, granulocytes, and endothelial cells. It plays a role in angiogenesis, wound healing, cellular migration, and signal transduction.

18613

Q08481

Mouse

390

Unconjugated

Primary Antibodies, Functional Antibodies

Cancer

The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.

Batch dependent

Phosphate-buffered aqueous solution, ph7.2.

None

Blue Ice

The product should be stored undiluted at 4˚ C . Do not freeze.

Rat IgG2a, kappa

The 390 monoclonal antibody specifically reacts with mouse cd31, a 130-140 kDA type I transmembrane glycoprotein also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1) .

Pecam1

Platelet/endothelial cell adhesion molecule 1

Mus musculus

HORENSTEIN, A., STOCKINGER, H., Imhof, B., MALAVASI, F. (1998) . CD38 binding to human myeloid cells is mediated by mouse and human CD31.Biochem. J,330, 1129-1135.

Baldwin, H. S., Shen, H. M., Yan, H. C., DeLisser, H. M., Chung, A., Mickanin, C., ... Albelda, S. M. (1994) . Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31) : alternatively spliced, functionally distinct isoforms expressed during mammalian cardiovascular development.Development,120 (9), 2539-2553.

DeLisser, H. M., Christofidou-Solomidou, M., Strieter, R. M., Burdick, M. D., Robinson, C. S., Wexler, R. S., ... Albelda, S. M. (1997) . Involvement of endothelial PECAM-1/CD31 in angiogenesis.The American journal of pathology,151 (3), 671.

Cd31, Pecam, C85791, PECAM-1, Pecam1

Flow, Functional Assays

Liquid