CD33 Antibody [WM53] (FITC)

The WM53 monoclonal antibody specifically reacts with human CD33, a 67 kDA transmembrane glycoprotein also known as GP67 and P67. CD33 is expressed on monocytes, granulocytes, dendritic cells, mast cells, and myeloid progenitors to the exclusion of hematopoietic stem cells, lymphocytes, and platelets. It functions to assist sialic acid-dependent cell adhesion.

945

P20138

Human

WM53

FITC

Primary Antibodies

Other

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Batch dependent

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

None

Blue Ice

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Mouse IgG1, kappa

The WM53 monoclonal antibody specifically reacts with human CD33, a 67 kDA transmembrane glycoprotein also known as GP67 and P67.

CD33

CD33 molecule

Homo sapiens

Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

Favaloro, E. J., Bradstock, K. F., Kabral, A., Grimsley, P., Zowtyj, H., Zola, H. (1988) . Further characterization of human myeloid antigens (gp160, 95; gp150; gp67) : investigation of epitopic heterogeneity and non‐haemopoietic distribution using panels of monoclonal antibodies belonging to CD‐11b, CD‐13 and CD‐33.British journal of haematology,69 (2), 163-171

Freeman, S. D., Kelm, S., Barber, E. K., Crocker, P. R. (1995) . Characterization of CD33 as a new member of the sialoadhesin family of cellular interaction molecules.Blood,85 (8), 2005-2012.

P67, SIGLEC3, SIGLEC-3, CD33

Flow

Liquid