CD33 Antilichaam [WM53]

CD33 is a 67 kDa type I transmembrane glycoprotein and a member of the sialoadhesin family of cell surface receptors. It is absent from pluripotent stem cells but appears on myelomonocytic precursors after CD34. It then continues to be expressed on both the myeloid and monocyte lineages. While it has been reported that CD33 can function as a sialic acid-dependent cell adhesion molecule, cells expressing CD33 require desialylation before they can bind cells bearing the appropriate sialoglycoconjugates. This suggests that inhibitory cis interactions may regulate or block any adhesion function.

945

P20138

P20138

Human

[WM53]

Unconjugated

Primary Antibodies

Immunology, Stem Cell

0.1 mg/mL

Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

None

Blue Ice

Store vial at 2-8˚ C

IgG1

CD33

CD33 Antibody [WM53] for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, immunoprecipitation, and blocking assays.

CD33

CD33 molecule

Homo sapiens

Gp67, p67, Siglec-3

WB, IHC-P, IHC-Fr, Flow, Blocking, IP

Liquid