CD35 Antilichaam [E11]

The CD35 antigen is composed of four different allotypes having different molecular weights [A (or F) - 160 kDa, B (or S) - 190 kDa, C - 220 kDa, and D - 250 kDa]. It is the receptor for C3b and is found on B cells, a subset of T cells, monocytes, neutrophils, follicular dendritic cells, erythrocytes, and kidney glomelular podocytes. CD35 mediates neutrophil and monocyte phagocytosis of particles coated with C3b and/or C4b. This interaction also enhances phagocytosis mediated by the Fc receptors.

1378

P17927

P17927

Human, Rhesus Monkey, Cynomolgus Monkey, Chimpanzee, Baboon

Acute monocytic leukemia cells and normal blood monocytes

[E11]

Unconjugated

Primary Antibodies

Immunology, Stem Cell

0.1 mg/mL

Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

None

Blue Ice

Store vial at 2-8˚ C

IgG1

CD35

CD35 Antibody [E11] for use in flow cytometry, immunohistochemistry, western blotting, ELISA, and immunoprecipitation assays.

CR1

Complement component (3b/4b) receptor 1 (Knops blood group)

Homo sapiens

CR1, complement receptor type 1, C3bR, C4bR, immune adherence receptor

Flow

Liquid