CD38 Antilichaam [90]

The 90 monoclonal antibody specifically bind to mouse CD38, a type II transmembrane glycoprotein. CD38 is expressed on activated T cells, plasma cells, monocytes, and macrophages. In the mouse as opposed to the human, CD38 expression is downregulated on mouse germinal center B cells and plasma cells. CD38 displays cyclase and hydrolase enzymatic activity and is involved in lymphocyte adhesion, activation, and cell signaling. Its ligand is CD31.

12494

P56528

Mouse

90

Unconjugated

Primary Antibodies, Functional Antibodies

Other

The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.

Batch dependent

Phosphate-buffered aqueous solution, ph7.2.

None

Blue Ice

The product should be stored undiluted at 4˚ C . Do not freeze.

Mouse IgG2a, kappa

The 90 monoclonal antibody specifically bind to mouse CD38, a type II transmembrane glycoprotein.

Cd38

CD38 antigen

Mus musculus

Gonzlez-lvaro, I., Domnguez-Jimnez, C., Ortiz, A. M., Nez-Gonzlez, V., Roda-Navarro, P., Fernndez-Ruiz, E., ... Snchez-Madrid, F. (2006) . Interleukin-15 and interferon- gammaparticipate in the cross-talk between natural killer and monocytic cells required for tumour necrosis factor production.Arthritis research therapy,8 (4), R88.

Katagiri, T., Qi, Z., Ohtake, S., Nakao, S. (2011) . GPI‐anchored protein‐deficient T cells in patients with aplastic anemia and low‐risk myelodysplastic syndrome: implications for the immunopathophysiology of bone marrow failure.European journal of haematology,86 (3), 226-236.

Yokoyama, S., Staunton, D., Fisher, R., Amiot, M., Fortin, J. J., Thorley-Lawson, D. A. (1991) . Expression of the Blast-1 activation/adhesion molecule and its identification as CD48.The Journal of immunology,146 (7), 2192-2200.

ADPRC 1, Cd38-rs1, Cd38

Flow, Functional Assays

Liquid