CD3e-antilichaam [C363.29B] (APC)

CD3epsilon, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chain ranging in size from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR) . It is expressed on all T cells of all mouse strains. CD3 plays a major role in signaling during antigen recognition, leading to T-cell activation. The monoclonal antibody C363.29B recognizes an epitope on the 25 kDa epsilon chain of the CD3/TCR complex. In the presence of Fc receptor-bearing accessory cells, soluble C363.29B can activate primed and naïve T cell in vitro. Immobilized C363.2B9 monoclonal antibody can also activate both normal T lymphocytes and cloned T cell lines provided the appropriate accessory signals are present. The monoclonal antibody is cytolytic, easily used for cell surface staining, and a good immunoprecipitating antibody.

12501

P22646

P22646

Mouse

IL-4 producing Th2 cell lines including D10

[C363.29B]

APC

Primary Antibodies

Immunology

0.1 mg/mL

Supplied in PBS/NaN3 and a stabilizing agent

None

Blue Ice

Store vial at 2-8˚ C

IgG2b

CD3epsilon

CD3e Antibody [C363.29B] for use in flow cytometry assays.

Cd3e

CD3 antigen, epsilon polypeptide

Mus musculus

CD3 epsilon

Flow

Liquid