CD3E Mouse Monoclonal Antibody [Kloon ID: UMLBI54]

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]

Carrier-free (BSA/glycerol-free) CD3E mouse monoclonal antibody, clone UMLBI54

IMD18; T3E; TCRE

Homo sapiens CD3e molecule (CD3E), mRNA.

916

P07766

Unconjugated

Hematopoietic cell lineage, Primary immunodeficiency, T cell receptor signaling pathway

Hematopoietic cell lineage, Primary immunodeficiency, T cell receptor signaling pathway

IHC 1:100, IF 1:100

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Transmembrane

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

CD3E

https://www.ncbi.nlm.nih.gov/gene/?term=916

https://www.uniprot.org/uniprot/P07766