CD4 Antilichaam [B486A1]

The CD4 antigen is highly expressed on human T helper cells and thymocytes, and at lower levels on monocytes and dendritic cells. This integral membrane glycoprotein of approximately 58 kDa contains four external domains (D1 to D4) that show homology to members of the immunoglobulin (Ig) superfamily. It is responsible for the recognition of the MHC class II antigen. The CD4 antibody recognizes most thymocytes and about 65% of peripheral blood T cells.

920

P01730

NP_000607.1

Human

Ni-NTA purified recombinant human CD4 expressed in E. Coli strain BL21 (DE3) .

B486A1

Unconjugated

Primary Antibodies

Immunology

Antibody is purified by protein A affinity chromatography.

Batch dependent

Purified antibody in PBS containing 0.03% sodium azide.

None

Blue Ice

CD4 monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG1

CD4

CD4 molecule

Homo sapiens

M Benkirane J Virol. 1995 November; 69 (11) : 6898¨C6903.

CD4mut

ELISA, WB, IHC

10835167