CD44 Antilichaam

Receptor for hyaluronic acid (HA) . Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs) . Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.

960

P16070

NP_000601.3

Human, Rat

CD44 antibody was raised against a peptide sequence around aa.734~738 (Q-N-V-D-M) derived from Human CD44.

Unconjugated

Primary Antibodies

Stem Cell

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

None

Blue Ice

Store antibody at -20˚ C for up to one year.

80 kDa

This antibody detects endogenous level of total CD44 protein.

Western Blot: 1:500~1:1000

CD44

CD44 molecule (Indian blood group)

Homo sapiens

Teriete P., et. al (2004) Mol. Cell 13:483-496 Bartolazzi A. (2003) Melanoma Res. 13:325-337Liu T. et. al (2005) J. Proteome Res. 4:2070-2080

IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1, CDW44, CSPG8, HCELL, HUTCH-I, ECMR-III

WB

48255935

Liquid