CD45R Antilichaam [RA3-6B2]

CD45R, also known as B220, a member of the protein tyrosine phosphate family and a major cell surface glycoprotein, represents a restricted form of the CD45 family which primarily recognizes only cells of B-lineage from pro-B cell through mature B lymphocytes and prior to the availability of anti-CD19 monoclonal antibodies was commonly used as a pan B-cell marker. It also reacts with certain activated T cells as well as non-MHC-restricted lytically active lymphokine-activated killer (LAK) cells. In vivo administration of RA3-6B2 has been shown to affect differentiation of both T and B cells in normal mice and reduce the level of anti-DNA antibodies and lymphadenopathies in MRL/lpr mice.

19264

P06800

P06800

Mouse, Human, Cat

Abelson murine leukemia virus-induced pre-B cell lymphoma

[RA3-6B2]

Unconjugated

Primary Antibodies

Immunology

0.5 mg/mL

Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

None

Blue Ice

Store vial at 2-8˚ C

IgG2a

CD45R

CD45R Antibody [RA3-6B2] for use in flow cytometry, immunohistochemistry, western blotting, immunoprecipitation, and blocking assays.

Ptprc

Protein tyrosine phosphatase, receptor type, C

Mus musculus

B220, Ly-5, Lyt-4, Ptprc, Receptor-type tyrosine-protein phosphatase C

Flow

Liquid