CD45RO Antilichaam [UCHL1] (APC)

The UCHL1 monoclonal antibody specifically reacts with human CD45RO, a 180 kDa isoform of the leukocyte common antigen CD45. CD45RO is a transmembrane glycoprotein with tyrosine phosphatase activity and is expressed by majority of thymocytes, monocytes, granulocytes, and activated memory T lymphocytes. The subsets of peripheral T lymphocytes can be discriminated by using the CD45RO and CD45RA expressing cells.

5788

P08575

Human

UCHL1

APC

Primary Antibodies

Immunology

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Batch dependent

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

None

Blue Ice

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Mouse IgG2a, kappa

The UCHL1 monoclonal antibody specifically reacts with human CD45RO, a 180 kDa isoform of the leukocyte common antigen CD45.

PTPRC

Protein tyrosine phosphatase, receptor type, C

Homo sapiens

Knapp W (1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

Akbar, A. N., Terry, L., Timms, A., Beverley, P. C., Janossy, G. (1988) . Loss of CD45R and gain of UCHL1 reactivity is a feature of primed T cells.The Journal of Immunology,140 (7), 2171-2178.

Smith, S. H., Brown, M. H., Rowe, D., Callard, R. E., Beverley, P. C. (1986) . Functional subsets of human helper-inducer cells defined by a new monoclonal antibody, UCHL1.Immunology,58 (1), 63.

LCA, LY5, B220, CD45, L-CA, T200, CD45R, GP180, PTPRC

Flow

Liquid