CD48 (NM 001778) Humaan Recombinant eiwit

This gene encodes a member of the CD2 subfamily of immunoglobulin-like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. The encoded protein is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells. The encoded protein does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

Purified recombinant protein of Human CD48 molecule (CD48), Gln27-Ser220, with N-terminal His tag, expressed in E. coli, 50ug

BCM1; BLAST; BLAST1; hCD48; mCD48; MEM-102; SLAMF2

962

P09326

NM_001778

1q23.3

E. coli

N-His

Natural killer cell mediated cytotoxicity

Natural killer cell mediated cytotoxicity

>50 ug/mL as determined by microplate BCA method

> 80% as determined by SDS-PAGE and Coomassie blue staining

Liquid

50mM Tris, 8M Urea, pH8.0.

Druggable Genome, Transmembrane

22.3 kDa

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

CD48

Human

NP_001769

https://www.ncbi.nlm.nih.gov/gene/962

https://www.uniprot.org/uniprot/P09326

https://www.ncbi.nlm.nih.gov/nuccore/NM_001778

https://www.ncbi.nlm.nih.gov/nuccore/NP_001769