CD49b Antilichaam [HAS-4]

CD49b, a member of the integrin family of extracellular matrix and cell adhesion molecules, is the integrin alpha2 chain. CD49b associates noncovalently with CD29, the integrin beta1 subunit, to form the heterodimer integrin alpha2beta1 that binds laminin and collagen. It is expressed on B and T lymphocytes, NK cells, monocytes, platelets, fibroblasts, and long-term cultured T cells. CD49b/CD29 mediates the Mg++-dependent adhesion of platelets to collagen. It may also be utilized by fibroblasts for the reorganization of the collagen matrix during wound healing.

3673

P17301

P17301

Human

Human keratinocytes

[HAS-4]

Unconjugated

Primary Antibodies

Cancer, Immunology, Obesity, Signal Transduction

0.1 mg/mL

Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

None

Blue Ice

Store vial at 2-8˚ C

IgG2a

CD49b

CD49b Antibody [HAS-4] for use in flow cytometry, immunohistochemistry / immunocytochemistry, immunoprecipitation, and blocking assays.

ITGA2

Integrin alpha-2

Homo sapiens

Integrin alpha2, VLA-2alpha, very late antigen-2

IHC-Fr, Flow

Liquid