CD49e Antilichaam [5H10.27]

The monoclonal antibody 5H10.27 reacts with the alpha5 chain (VLA-5) of the CD49e/CD29 heterodimeric fibronectin receptor. It is expressed on thymocytes, activated T cells, mast cells, and a variety of mouse cell lines. Soluble 5H10.27 antibody inhibits VLA-5-mediated functions in vitro. Immobilized 5H10.27 has also been demonstrated to costimulate the proliferative response of CD8+ T cells to plate-bound anti-CD3 monoclonal antibody.

16402

P11688

P11688

Mouse

C57BL/6 x A/J F1 mouse mast cell line MC/9

[5H10.27]

Unconjugated

Primary Antibodies

Cancer, Signal Transduction

0.5 mg/mL

Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

None

Blue Ice

Store vial at 2-8˚ C

IgG2a

CD49e

CD49e Antibody [5H10.27] for use in flow cytometry, immunohistochemistry, costimulation, blocking, and adhesion assays.

Itga5

Integrin alpha 5 (fibronectin receptor alpha)

Mus musculus

Integrin alpha5, VLA-5alpha

Flow

Liquid