CD51 Antilichaam (13C2]

CD51 represents the integrin alphaV chain that associates with integrin beta3 (CD61) to form the CD51/CD61 vitronectin receptor on endothelial cells, certain activated leukocytes, NK cells, macrophages, neutrophils, and platelets. CD51 is the most promiscuous integrin alpha subunit as it can form heterodimers with the beta1 (CD29), beta3 (CD61), beta5, beta6 and beta8 subunits in various tissues. CD51/CD61 acts as an activation-independent receptor for platelet attachment and spreading on vitronectin and other RGD-containing proteins including matrix components. It also mediates leukocyte-endothelial cell adhesion via interaction with CD31.

3685

P06756

P06756

Human, African Green Monkey, Rabbit, Bovine

Cell suspension containing osteoclasts from osteoclastomas

[13C2]

Unconjugated

Primary Antibodies

Other

0.1 mg/mL

Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

None

Blue Ice

Store vial at 2-8˚ C

IgG1

CD51

CD51 Antibody [13C2] for use in flow cytometry, immunohistochemistry / immunocytochemistry, immunoprecipitation, ELISA, purification, depletion, adhesion, and blocking assays.

ITGAV

Integrin, alpha V

Homo sapiens

Integrin alphaV, vitronectin receptor, VNR-alpha chain

Flow

Liquid