CD59 Polyklonale Antilichaam, Biotin Vervoeging

Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes.

1F5; EJ16; EJ3; EL32; G344; MIN1; MIN2; MIN3; MIRL; HRF2; MACIF; MEM43; MIC11; MSK21; 16.3A5; HRF-2; MAC-IP; p18-2; CD59 glycoprotein; 1F5 antigen; 2 kDa homologous restriction factor; MAC-inhibitory protein; MEM43 antigen; Membrane attack complex inhibition factor; Membrane inhibitor of reactive lysis; Protectin; CD59

966

P13987

Cell membrane

Human

52-100/128

CD59

Biotin

KLH conjugated synthetic peptide derived from human CD59

ELISA, IHC-P, IHC-F

Purified by Protein A.

1µg/µl

ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C for 12 months.

966