CD61 Antilichaam [2C9.G3]

The 2C9.G3 monoclonal antibody specifically reacts with the mouse/rat CD61 molecule, known as the integrin beta 3 that forms the vitronectin receptor with CD51. The complex binds to other ligands such as fibrinogen, fibronectin, thrombospondin, and von WIllebrand factor. It is expressed by granulocytes, platelets, activated T cells, smooth muscle, and a subset of B cells.

16416

O54890

Mouse, Rat

2C9.G3

Unconjugated

Primary Antibodies, Functional Antibodies

Immunology

The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.

Batch dependent

Phosphate-buffered aqueous solution, ph7.2.

None

Blue Ice

The product should be stored undiluted at 4˚ C . Do not freeze.

Armenian Hamster IgG

The 2C9.G3 monoclonal antibody specifically reacts with the mouse/rat CD61 molecule, known as the integrin beta 3 that forms the vitronectin receptor with CD51.

Itgb3

Integrin beta 3

Mus musculus

Vaillant, F., Asselin-Labat, M. L., Shackleton, M., Forrest, N. C., Lindeman, G. J., Visvader, J. E. (2008) . The mammary progenitor marker CD61/-beta 3 integrin identifies cancer stem cells in mouse models of mammary tumorigenesis.Cancer research,68 (19), 7711-7717.

Yasuda, M., Hasunuma, Y., Adachi, H., Sekine, C., Sakanishi, T., Hashimoto, H., ... Okumura, K. (1995) . Expression and function of fibronectin binding integrins on rat mast cells.International immunology,7 (2), 251-258.

Wu, X., Mogford, J. E., Platts, S. H., Davis, G. E., Meininger, G. A., Davis, M. J. (1998) . Modulation of calcium current in arteriolar smooth muscle by alpha v-beta 3 and alpha 5-beta 1 integrin ligands.The Journal of cell biology,143 (1), 241-252.

CD61, GP3A, INGRB3, Itgb3

Flow, Functional Assays

Liquid