CD62P Antilichaam (AK-4] (PE)

The AK-4 monoclonal antibody specifically reacts with human CD62P (P-Selectin), a 140 kDA type I transmembrane glycoprotein also known as platelet activation-dependent granule membrane protein (PADGEM) . Upon activation it is quickly transported to the plasma membrane from the alpha-granules of platelets and WEibel-Palade bodies of endothelial cells. It is essential to the functions of cell adhesion during inflammatory reactions and in the interaction of platelets with monocytes and neutrophils.

6403

P16109

Human

AK-4

PE

Primary Antibodies

Immunology

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Batch dependent

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

None

Blue Ice

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Mouse IgG1, kappa

The AK-4 monoclonal antibody specifically reacts with human CD62P (P-Selectin), a 140 kDA type I transmembrane glycoprotein also known as platelet activation-dependent granule membrane protein (PADGEM) .

SELP

Selectin P (granule membrane protein 140kDa, antigen CD62)

Homo sapiens

Leucocyte Typing VI: White Cell Differentiation Antigens: Proceedings of the Sixth International Workshop and Conference Held in Kobe, Japan, 10-14 November 1996. Garland Pub., 1998.

Schlossman, S. F. (1995) .Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.

Johnson-Tidey, R. R., McGregor, J. L., Taylor, P. R., Poston, R. N. (1994) . Increase in the adhesion molecule P-selectin in endothelium overlying atherosclerotic plaques. Coexpression with intercellular adhesion molecule-1.The American journal of pathology,144 (5), 952.

CD62, GRMP, PSEL, CD62P, GMP140, LECAM3, PADGEM, SELP

Flow

Liquid